Aniracetam
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Aniracetam has been shown to positively modulate the AMPA receptor.
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Aniracetam has been shown to positively modulate the AMPA receptor.
When ingested orally aniracetam is quickly broken down via first pass hepatic metabolism. The primary metabolites of aniracetam are N-anisoyl-GABA, (70?80%), 2-Pyrrolidinone and p-anisic acid (20?30%).
Plasma concentrations are generally in the 5?15 ?g/L range for aniracetam and 5?15 mg/L range for N-anisoyl-GABA, a pharmacologically-active metabolite, during the first few hours after oral administration of the drug. These two plasma species may be measured by liquid chromatography-mass spectrometry
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